Buy Cymbalta Online

Cymbalta

Cymbalta is the brand name of the drug called duloxetine. It is selective serotonin and nor epinephrine reuptake inhibitor known as SNRIs. It is used for treating anxiety disorder, fibromyalgia, major depressive disorder and neuropathic pain. It was produced by Eli Lilly.

Mechanism of action

Cymbalta stops the reuptake of serotonin and nor epinephrine in the central nervous system (CNS). Cymbalta increases dopamine preferably in the prefrontal cortex, there are few dopamine reuptake pumps, through the inhibition of or epinephrine reuptake pumps. Depression is believed to happen because of increase in pro-inflammatory cytokines so what Cymbalta does is it decreases the activity of pro inflammatory cytokines in the central nervous system.

Cymbalta stops the reuptake of serotonin

Uses

Cymbalta is mainly used in major depressive disorder, anxiety disorder, fibromyalgia (a chronic pain disorder), neuropathic pain, chronic muscle or joint pain and diabetic neuropathy (nerve damage in patients with diabetes).

Dosage and administration

Cymbalta comes in tablet or capsule form. You can take it with water with or without food but do not chew or crush the pill as it can dim its effectiveness and may damage your enteric coating. Do not take two doses together if you miss a dose instead take your medicine whenever you remember?

It is given as 40mg or 60mg twice a day (either 20mg twice or 30mg twice a day) 60mg is the maximum dose given. It was once thought that 120mg dose is effective but due to no evidence, it is not preferred. If you think you need to reassess the dosage consult your doctor.

Side-effects

These are some of the rare side-effect:

  • Abdominal pain
  • area rash
  • blindness
  • blurred vision
  • chills
  • clay-colored stools
  • cold sweats
  • confusion
  • convulsions
  • dark urine
  • decreased urine output
  • decreased vision
  • difficulty swallowing
  • increased thirst
  • joint or muscle pain
  • swelling on the face, tongue, lips, eyelids, or sex organs
  • light-colored stool
  • loss of consciousness
  • red skin lesion

Some of the common side-effects:

  • Body aches
  • difficulty in stool
  • cough
  • ear congestion
  • dry mouth
  • headache
  • frequent urination
  • muscle ache
  • unusual drowsiness
  • nausea
  • sore throat
  • sleepiness
  • sweating increased
  • sneezing
  • runny nose

Precaution and warning

If you have any allergic reactions please tell your doctor about it before taking this medication as it has some inactive ingredient that may be harmful. Also, share your full family history to doctor before taking this medication. Do not consume alcohol while on this medication as it makes you drowsy.

Pregnancy and breastfeeding

It is not recommended because the studies show some teratogenicity to the fetus. It is also excreted into the milk therefore not recommended while lactation.

Drug interaction

Drugs like warfarin, NSAIDS, clopidogrel, ibuprofen are some of the drugs that should not be used with Cymbalta.